RPS14 : ribosomal protein S14
Description
The RPS14 (ribosomal protein S14) is a protein-coding gene located on chromosome 5.
The RPS14 gene provides instructions for making one of approximately 80 different ribosomal proteins, which are components of cellular structures called ribosomes. Ribosomes process the cell's genetic instructions to create proteins. Each ribosome is made up of two parts (subunits) called the large and small subunits. The protein produced from the RPS14 gene is among those found in the small subunit. The specific functions of the RPS14 protein and the other ribosomal proteins within these subunits are unclear. Some ribosomal proteins are involved in the assembly or stability of ribosomes. Others help carry out the ribosome's main function of building new proteins. Studies suggest that some ribosomal proteins may have other functions, such as participating in chemical signaling pathways within the cell, regulating cell division, and controlling the self-destruction of cells (apoptosis).
RPS14 is also known as EMTB, S14, uS11.
Associated Diseases
- Chromosome 5q deletion syndrome
- Myelodysplastic syndrome associated with isolated del(5q) chromosome abnormality
- 5q minus syndrome
