RINL
Description
The RINL (Ras and Rab interactor like) is a protein-coding gene located on chromosome 19.
RINL acts as a guanine nucleotide exchange factor (GEF) for RAB5A and RAB22A. It facilitates the activation of these Rab proteins by replacing bound GDP with GTP. This process plays a crucial role in endocytosis, a cellular mechanism for taking in materials from the outside.
RINL is also known as -.
Associated Diseases
- alpha thalassemia-intellectual disability syndrome type 1
- hemolytic anemia due to adenylate kinase deficiency
- Heinz body anemia
- hereditary persistence of fetal hemoglobin-sickle cell disease syndrome
- delta-beta-thalassemia
- IRIDA syndrome
- hemoglobin C-beta-thalassemia syndrome
- hemoglobin D disease
- hemoglobin E-beta-thalassemia syndrome
- dominant beta-thalassemia
- Rh deficiency syndrome
- hereditary spherocytosis type 3
- pyropoikilocytosis, hereditary
- alpha-thalassemia-myelodysplastic syndrome
- overhydrated hereditary stomatocytosis
