RIC8B

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Description

The RIC8B (RIC8 guanine nucleotide exchange factor B) is a protein-coding gene located on chromosome 12.

RIC8B is a guanine nucleotide exchange factor (GEF) that activates certain G-alpha proteins by replacing bound GDP with GTP. This protein is involved in olfactory signaling, specifically enhancing G(olf)-alpha-dependent cAMP accumulation. This suggests a crucial role in odorant signal transduction.

RIC8B is also known as RIC8, hSyn.

Associated Diseases