RBM11
Description
The RBM11 (RNA binding motif protein 11) is a protein-coding gene located on chromosome 21.
RBM11 is a protein encoded by the RBM11 gene in humans. It acts as a splicing regulator.
RBM11 is a tissue-specific splicing factor that plays a role in regulating alternative splicing during the development of neurons and germ cells. It acts as an antagonist to SRSF1, a protein that promotes splicing. RBM11 can influence the selection of alternative 5' splice sites by binding to specific sequences within exons and counteracting the activity of SRSF1.
RBM11 is also known as -.
Associated Diseases
- linear and whorled nevoid hypermelanosis
- eosinophil peroxidase deficiency
- neutropenia, severe congenital, 1, autosomal dominant
- idiopathic hypereosinophilic syndrome
- ichthyosis prematurity syndrome
- cancer
- glioblastoma
