RASA4B

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Description

The RASA4B (RAS p21 protein activator 4B) is a protein-coding gene located on chromosome 7.

The RASA4B gene encodes for a protein known as RAS p21 protein activator 4B in humans.

RASA4B is a calcium-dependent Ras GTPase-activating protein (GAP) that may be involved in the Ras-MAPK signaling pathway.

RASA4B is also known as -.

Associated Diseases

• isolated agammaglobulinemia
• immune deficiency, familial variable
• hyper-IgM syndrome type 2
• recurrent Neisseria infections due to factor D deficiency
• immunodeficiency 28
• common variable immunodeficiency
• type 2 diabetes mellitus
• immunodeficiency, common variable, 4
• mannose-binding lectin deficiency
• type II complement component 8 deficiency
• hyper-IgM syndrome type 5
• hyper-IgM syndrome type 3
• autosomal recessive primary immunodeficiency with defective spontaneous natural killer cell cytotoxicity
• immunodeficiency due to ficolin3 deficiency
• immunodeficiency 33