RAMP3
Description
The RAMP3 (receptor activity modifying protein 3) is a protein-coding gene located on chromosome 7.
RAMP3, also known as Receptor activity modifying protein 3, is a human gene. The protein encoded by this gene is part of the RAMP family of single-transmembrane-domain proteins. RAMPs help guide the calcitonin-receptor-like receptor (CRLR) to the cell surface. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. There are 3 RAMPs in humans and other mammals, and more in fish, including sub-variants. In the presence of RAMP3, CRLR acts as an adrenomedullin receptor with low affinity for CGRP.
RAMP3 is also known as -.
