RAB9A
Description
The RAB9A (RAB9A, member RAS oncogene family) is a protein-coding gene located on chromosome X.
RAB9A is a protein encoded by the RAB9A gene in humans. It interacts with proteins such as RABEPK, TIP47, and the Biogenesis of lysosome-related organelles complex 3.
RAB9A plays a crucial role in the movement of proteins between endosomes and the trans Golgi network. It also facilitates the recruitment of SGSM2 to melanosomes, ensuring the correct delivery of melanogenic enzymes (TYR, TYRP1, and DCT/TYRP2) to melanosomes within melanocytes.
RAB9A is also known as RAB9.
Associated Diseases
- lysosomal storage disease
- Alzheimer disease
- Parkinson disease
- multiple sclerosis
- Niemann-Pick disease type C
- cancer
