RAB17
Description
The RAB17 (RAB17, member RAS oncogene family) is a protein-coding gene located on chromosome 2.
RAB17 is a protein that is encoded by the RAB17 gene in humans. It is a member of the Ras-related protein Rab family.
RAB17 is a member of the Rab family of small GTPases, which are key regulators of intracellular membrane trafficking. RAB17 cycles between an inactive GDP-bound form and an active GTP-bound form, which recruits downstream effectors to membranes. This protein is involved in transcytosis, the directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side, primarily in epithelial cells. RAB17 is also required for melanosome transport and release from melanocytes and may play a role in cell migration. Additionally, it regulates dendrite and dendritic spine development.
RAB17 is also known as -.
