PURG
Description
The PURG (purine rich element binding protein G) is a protein-coding gene located on chromosome 8.
The PURG gene in humans creates a protein called Purine-rich element binding protein G. While the exact function of this protein isn't known, it shares strong similarities with another protein called PURA. PURA binds to DNA, specifically to areas rich in purines, and plays a role in controlling both DNA replication and gene activity. The PURG gene is found close to the Werner syndrome gene on chromosome 8, but on the opposite strand. Two versions of the PURG gene have been identified, each producing a slightly different form of the protein.
The exact role of the PURG gene is not fully understood. However, the protein it produces is very similar to another protein called PURA, which is known to bind to DNA, particularly to areas rich in purine bases, called 'PUR elements'. This binding activity suggests that PURG might also be involved in regulating how genes are copied and used, similar to PURA. It's important to note that PURG is located on chromosome 8 near the gene responsible for Werner syndrome, a genetic disorder related to premature aging.
PURG is also known as PURG-A, PURG-B, PURGA, PURGB.
