PPFIA4
Description
The PPFIA4 (PTPRF interacting protein alpha 4) is a protein-coding gene located on chromosome 1.
Liprin-alpha-4 is a protein that in humans is encoded by the PPFIA4 gene.
PPFIA4 has been shown to interact with:
ERC2, GIT1, and Nuclear receptor coactivator 2.
PPFIA4 may play a role in regulating the disassembly of focal adhesions. It might also localize receptor-like tyrosine phosphatases type 2A to specific areas of the plasma membrane, potentially influencing their interaction with the extracellular environment and their binding to substrates.
PPFIA4 is also known as -.
Associated Diseases
- asthma
- childhood onset asthma
- corneal endothelial dystrophy
- keratoconus 1
- X-linked endothelial corneal dystrophy
- keratoconus
- Schnyder corneal dystrophy
- macular corneal dystrophy
- ring dermoid of cornea
- congenital stromal corneal dystrophy
- cornea plana 2
