PPAP2C
PPAP2C Gene: An Essential Regulator in the Fight Against Disease
Description
The PPAP2C gene, also known as the phosphatidic acid phosphatase type 2C gene, plays a crucial role in cellular processes vital for our health. It encodes an enzyme that catalyzes the dephosphorylation of phosphatidic acid, a lipid molecule involved in various cellular functions, including cell growth, differentiation, and apoptosis.
Associated Diseases
Mutations or dysregulation of the PPAP2C gene have been linked to several human diseases, including:
- Neurodegenerative diseases: Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS)
- Metabolic disorders: Type 2 diabetes and obesity
- Cardiovascular disease: Heart failure and arrhythmias
- Cancer: Prostate cancer, breast cancer, and leukemia
Did you Know ?
Studies have shown that individuals with certain variations in the PPAP2C gene have a significantly increased risk of developing Alzheimer's disease. Researchers estimate that these genetic variations may account for up to 10% of cases of late-onset Alzheimer's.
