POU3F4 : POU class 3 homeobox 4
Description
The POU3F4 (POU class 3 homeobox 4) is a protein-coding gene located on chromosome X.
The POU3F4 gene provides instructions for making a protein that helps regulate the activity of other genes. This protein, called a transcription factor, is part of a larger family of transcription factor genes known as POU domain genes. These genes play a role in determining cell types in the brain and spinal cord during early development. The proteins produced from these genes each contain two regions, called the POU-specific domain and POU homeodomain, which bind to the DNA of other genes. The POU3F4 protein is likely involved in the development of the middle and inner ear, and it is also active in certain regions of the brain before birth. Researchers are working to determine which genes are regulated by this protein.
The POU3F4 protein likely acts as a transcription factor, primarily during early neural development and in a limited number of mature brain neurons.
POU3F4 is also known as BRAIN-4, BRN-4, BRN4, DFN3, DFNX2, OCT-9, OTF-9, OTF9.
