POU3F1


Description

The POU3F1 (POU class 3 homeobox 1) is a protein-coding gene located on chromosome 1.

POU domain, class 3, transcription factor 1 (also known as Oct-6) is a protein that in humans is encoded by the POU3F1 gene. It is a transcription factor involved in the regulation of gene expression.

POU3F1 is a transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). It acts as a transcriptional activator when binding cooperatively with SOX4, SOX11, or SOX12 to gene promoters. It also acts as a transcriptional repressor of myelin-specific genes.

POU3F1 is also known as OCT6, OTF6, SCIP.

Associated Diseases



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