PORCN : porcupine O-acyltransferase
Description
The PORCN (porcupine O-acyltransferase) is a protein-coding gene located on chromosome X.
The PORCN gene provides instructions for making a protein that belongs to a group of related proteins called the porcupine (Porc) family. While the exact function of the PORCN protein is not fully understood, proteins in the Porc family are involved in transferring a molecule called palmitoleic acid to Wnt proteins. Wnt proteins are essential for signaling pathways in the body and play critical roles in development before birth. Members of the Porc family are located in the endoplasmic reticulum, a structure inside the cell responsible for protein processing and transport. The transfer of palmitoleic acid to Wnt proteins allows these proteins to be released from the cell, enabling them to regulate the development of skin, bones, and other structures. Researchers are actively investigating the specific role of the PORCN protein within human cells.
PORCN is also known as DHOF, FODH, MG61, PORC, PPN.
