PNRC1
Description
The PNRC1 (proline rich nuclear receptor coactivator 1) is a protein-coding gene located on chromosome 6.
Proline-rich nuclear receptor coactivator 1 (PNRC1) is a protein encoded by the PNRC1 gene in humans. PNRC1 acts as a coactivator for numerous nuclear receptors, including AR, ERα, ERRα, ERRγ, GR, SF1, PR, TR, RAR, and RXR. This interaction relies on the SH3 domain present in PNRC1.
PNRC1 functions as a coactivator for nuclear receptors, potentially contributing to signal transduction.
PNRC1 is also known as B4-2, PNAS-145, PROL2, PRR2.
Associated Diseases
- COVID-19
- Gerstmann-Straussler-Scheinker syndrome
- nonpapillary renal cell carcinoma
- type 1 diabetes mellitus
- cancer
