PLET1

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Description

The PLET1 (placenta expressed transcript 1) is a protein-coding gene located on chromosome 11.

PLET1 protein influences how keratinocytes move and attach to surrounding tissues during wound healing, promoting the repair process. It might also be involved in the development of a specific hair follicle cell type.

PLET1 is also known as C11orf34.

Associated Diseases

• hyperinsulinism due to INSR deficiency
• hyperinsulinism due to glucokinase deficiency
• hypoparathyroidism, familial isolated, 2
• exercise-induced hyperinsulinism
• hyperinsulinism-hyperammonemia syndrome
• pseudohypoparathyroidism type 2
• isolated agammaglobulinemia
• isolated hyperchlorhidrosis
• familial hyperaldosteronism type II
• hyperinsulinemic hypoglycemia, familial, 4
• hyperinsulinemic hypoglycemia, familial, 1
• pseudohypoaldosteronism, type IB2, autosomal recessive
• corticosterone methyloxidase type 2 deficiency
• hearing loss-familial salivary gland insensitivity to aldosterone syndrome
• islet cell adenomatosis
• hyperinsulinemic hypoglycemia, familial, 2