PIM1
The PIM1 Gene: A Key Player in Cancer and Beyond
Description
The PIM1 gene encodes a protein known as PIM1 kinase, a critical regulator of cell proliferation, survival, and differentiation. It is involved in various cellular processes, including protein synthesis, cell division, and apoptosis. Overexpression of PIM1 has been implicated in cancer development, as it promotes tumor cell growth, inhibits apoptosis, and enhances angiogenesis.
Associated Diseases
PIM1 overexpression has been linked to several types of cancer, including:
- Prostate cancer
- Breast cancer
- Lung cancer
- Colon cancer
- Lymphoma
In addition to cancer, dysregulation of PIM1 has been associated with other diseases, such as:
- Autoimmune disorders
- Cardiovascular diseases
- Metabolic disorders
Did you Know ?
Overexpression of PIM1 is found in approximately 30% of all human cancers. This highlights the significant role of PIM1 in cancer development and progression.
