PHF23

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Description

The PHF23 (PHD finger protein 23) is a protein-coding gene located on chromosome 17.

PHF23 acts as a negative regulator of autophagy by promoting the ubiquitination and degradation of LRSAM1. LRSAM1 is an E3 ubiquitin ligase that triggers autophagy in response to starvation or bacterial infection.

PHF23 is also known as hJUNE-1b.

Associated Diseases