PFDN2

Description

The PFDN2 (prefoldin subunit 2) is a protein-coding gene located on chromosome 1.

Prefoldin subunit 2 is a protein that in humans is encoded by the PFDN2 gene. This gene encodes a member of the prefoldin beta subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils.

Prefoldin subunit 2 (PFDN2) acts as a molecular chaperone by binding to newly synthesized polypeptide chains, promoting their correct folding and facilitating their transfer to the cytosolic chaperonin (c-CPN) for further processing.

PFDN2 is also known as PFD2.

Associated Diseases


Login to View More

Related Products

WES Whole Exome Sequencing

Disclaimer: The information provided here is not exhaustive by any means. Always consult your doctor or other qualified healthcare provider with any questions you may have regarding a medical condition, procedure, or treatment, whether it is a prescription medication, over-the-counter drug, vitamin, supplement, or herbal alternative.