PCNA-AS1
Description
The PCNA-AS1 (PCNA antisense RNA 1) is a ncRNA gene located on chromosome 20.
PCNA-AS1 is a long non-coding RNA (lncRNA) that is involved in regulating cell proliferation, DNA replication, and tumorigenesis. It has been shown to promote cell growth and tumor development in various cancer types.
PCNA-AS1 (Proliferating Cell Nuclear Antigen-antisense RNA 1) is a long non-coding RNA (lncRNA) that plays a crucial role in regulating cell proliferation, DNA replication, and tumorigenesis. It acts as a molecular sponge, sequestering microRNAs (miRNAs) and modulating their activity, thereby impacting the expression of target genes. Studies have shown that PCNA-AS1 can promote cell growth and tumor development in various cancer types, including colorectal cancer, breast cancer, and gastric cancer. Its expression levels are often elevated in tumor cells and associated with poor prognosis. Moreover, PCNA-AS1 has been implicated in DNA damage response and repair, suggesting its involvement in maintaining genomic stability.
PCNA-AS1 is also known as PCNA-AS, PCNAAS.
