PCDHB11
Description
The PCDHB11 (protocadherin beta 11) is a protein-coding gene located on chromosome 5.
PCDHB11 is a gene located on chromosome 5 and is part of the protocadherin beta gene cluster. This cluster contains 16 genes and 3 pseudogenes, each encoding a protein with 6 extracellular cadherin domains and a unique cytoplasmic tail. These proteins are involved in cell-cell adhesion and likely play a vital role in establishing and maintaining specific neural connections. Unlike other protocadherin clusters, the transcripts from the beta cluster are made up of only one large exon, not sharing common 3' exons. These proteins are integral plasma membrane proteins, suggesting their involvement in cell-cell interactions and signaling. Although their specific functions remain unclear, their presence in the brain suggests a critical role in neural development and function.
PCDHB11 is also known as ME2, PCDH-BETA11.
