PARVA
Description
The PARVA (parvin alpha) is a protein-coding gene located on chromosome 11.
Alpha-parvin is a protein that in humans is encoded by the PARVA gene.
PARVA plays a crucial role in various cellular processes, including sarcomere organization, smooth muscle contraction, embryonic cardiovascular development, heart outflow tract septation, sprouting angiogenesis, vascular smooth muscle cell adhesion, actin cytoskeleton reorganization, lamellipodia formation, ciliogenesis, cell polarity establishment, cell adhesion, cell spreading, and directed cell migration.
PARVA is also known as CH-ILKBP, MXRA2.
Associated Diseases
- amelogenesis imperfecta
- immunodeficiency 75
- idiopathic hypereosinophilic syndrome
- hemoglobin H disease
- dominant beta-thalassemia
- glycoprotein storage disease
- dentin dysplasia type I
