PAPOLG
Description
The PAPOLG (poly(A) polymerase gamma) is a protein-coding gene located on chromosome 2.
PAPOLG encodes a poly(A) polymerase enzyme that adds adenine nucleotides to the 3' end of DNA or RNA strands. It is similar to poly(A) polymerase II (PAPII) but is located on chromosome 2 instead of chromosome 14. PAPOLG is found only in the nucleus and can add adenine nucleotides both with and without the help of the CPSF protein.
PAPOLG is responsible for adding adenine nucleotides to the 3' end of mRNA precursors and several small RNAs, including signal recognition particle (SRP) RNA, nuclear 7SK RNA, U2 small nuclear RNA, and ribosomal 5S RNA.
PAPOLG is also known as -.
