OSTF1

• SHARE NOW |
• Tweet Opens in a new window.
• Pin it Opens in a new window.
• Share Opens in a new window.
• Share Opens in a new window.
• Email Opens in a new window.

---

Description

The OSTF1 (osteoclast stimulating factor 1) is a protein-coding gene located on chromosome 9.

Osteoclast-stimulating factor 1 is a protein produced by the OSTF1 gene in humans.

OSTF1 promotes bone resorption. It likely works through a chain of signals that lead to the release of substances that encourage osteoclast formation and activity.

OSTF1 is also known as OSF, SH3P2, bA235O14.1.

Associated Diseases

• X-linked retinal dysplasia
• Gorham-Stout disease
• melorheostosis
• retinitis pigmentosa
• dacryocystitis-osteopoikilosis syndrome
• 12q14 microdeletion syndrome
• pyknoachondrogenesis
• microphthalmia with limb anomalies
• osteosclerosis-ichthyosis-premature ovarian failure syndrome
• osteomesopyknosis
• severe early-childhood-onset retinal dystrophy
• reticular dystrophy of the retinal pigment epithelium
• hyperostosis corticalis generalisata