ORAI3

Description

The ORAI3 (ORAI calcium release-activated calcium modulator 3) is a protein-coding gene located on chromosome 16.

ORAI3 is a protein that forms part of calcium channels in cell membranes. These channels are essential for regulating the flow of calcium ions into cells, which plays a crucial role in various cellular processes, including muscle contraction, nerve signaling, and immune responses. ORAI3 works together with other proteins, particularly STIM1, to control the activity of these channels.

ORAI3 is a subunit of Ca(2+) release-activated Ca(2+)-like (CRAC-like) channels that control calcium influx into cells. It works together with the calcium sensor STIM1 to increase the flow of calcium ions through the channel.

ORAI3 is also known as TMEM142C.

Associated Diseases


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