OR4M1
Description
The OR4M1 (olfactory receptor family 4 subfamily M member 1) is a protein-coding gene located on chromosome 14.
Olfactory receptor 4M1 is a protein encoded by the OR4M1 gene in humans. Olfactory receptors are responsible for detecting odorant molecules in the nose, initiating a neuronal response that leads to smell perception. They belong to the large family of G-protein-coupled receptors (GPCRs) and share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors. These receptors are crucial for recognizing and transducing odorant signals through G proteins. The olfactory receptor gene family is the largest in the human genome, with a unique nomenclature system.
OR4M1 is also known as OLFR734, OR14-7.
Associated Diseases
- thyroid gland adenocarcinoma
- low grade glioma
- PLIN1-related familial partial lipodystrophy
- obesity due to melanocortin 4 receptor deficiency
- CIDEC-related familial partial lipodystrophy
- obesity due to prohormone convertase I deficiency
- PPARG-related familial partial lipodystrophy
- AKT2-related familial partial lipodystrophy
- LIPE-related familial partial lipodystrophy
- obesity due to congenital leptin deficiency
- obesity due to leptin receptor gene deficiency
- galactokinase deficiency
- glycogen storage disease VI
- hyperinsulinism due to HNF1A deficiency
- familial partial lipodystrophy, Dunnigan type
- hypoinsulinemic hypoglycemia and body hemihypertrophy
- obesity due to pro-opiomelanocortin deficiency
- congenital generalized lipodystrophy type 2
