OR1A2
Description
The OR1A2 (olfactory receptor family 1 subfamily A member 2) is a protein-coding gene located on chromosome 17.
Olfactory receptor 1A2 is a protein encoded by the OR1A2 gene in humans. It's a member of the large family of G-protein-coupled receptors (GPCRs) involved in smell perception. These receptors bind to odorant molecules in the nose, initiating a neuronal response that triggers the sense of smell. The OR1A2 protein shares a common 7-transmembrane domain structure with other GPCRs involved in neurotransmitter and hormone signaling. The olfactory receptor gene family is the largest in the human genome. The OR1A2 gene is named independently from other organisms. Known ligands for OR1A2 include various compounds with citrus or fruity smells, such as citronellal, helional, heptanal, octanal, nonanal, hydroxycitronellal, citral, and citronellol.
This protein is an odorant receptor, a type of G protein-coupled receptor (GPCR), that detects and binds to odorant molecules in the nose. This binding triggers a signal cascade that leads to the perception of smell.
OR1A2 is also known as OR17-6.
