NXF2
Description
The NXF2 (nuclear RNA export factor 2) is a protein-coding gene located on chromosome X.
NXF2 (Nuclear RNA export factor 2) is a protein encoded by the NXF2 gene in humans. It belongs to a family of nuclear RNA export factors and plays a crucial role in mRNA export. NXF2 is located in the nucleoplasm and is associated with the nuclear envelope. Alternative splicing is common in this gene family, and two variants have been identified for NXF2. NXF2 has been shown to interact with NUP214.
NXF2 facilitates the transport of messenger RNA (mRNA) from the nucleus to the cytoplasm.
NXF2 is also known as CT39, TAPL-2, TCP11X2.
Associated Diseases
- partial chromosome Y deletion
- male infertility with teratozoospermia due to single gene mutation
- spermatogenic failure 25
- spermatogenic failure 63
- spermatogenic failures 50
- isochromosomy Yp
- spermatogenic failure, X-linked, 2
- spermatogenic failure 65
- spermatogenic failure 48
- spermatogenic failure, X-linked, 3
- spermatogenic failure 40
- spermatogenic failure 47
- spermatogenic failure 73
- spermatogenic failure 74
- spermatogenic failure 7
- spermatogenic failure 61
- spermatogenic failure 10
- spermatogenic failure 11
- spermatogenic failure 39
- congenital bilateral absence of vas deferens
- spermatogenic failure 41
- spermatogenic failure 72
