NTSR1
Title: NTRK1: A Promising Target for Precision Cancer Therapy
Description:
NTRK1 is a gene that encodes a protein called neurotrophic tyrosine kinase receptor 1. This receptor plays a crucial role in regulating growth and survival signals in cells. Mutations in the NTRK1 gene lead to the production of abnormal NTRK1 proteins, which can drive tumor growth in a variety of cancers.
Associated Diseases:
Mutations in the NTRK1 gene have been associated with several types of cancer, including:
- Infantile fibrosarcoma
- Pancreatic cancer
- Colorectal cancer
- Lung cancer
- Melanoma
Did you Know ?
NTRK1 mutations are found in approximately 1% of all solid tumors. However, in certain subtypes of cancer, such as infantile fibrosarcoma, NTRK1 mutations are present in up to 90% of cases.
