NPPC

Description

The NPPC (natriuretic peptide C) is a protein-coding gene located on chromosome 2.

NPPC may refer to:

CNP-22 is a hormone that plays a role in endochondral ossification by regulating the proliferation and differentiation of chondrocytes in the cartilaginous growth plate. It may also have vasoactive and natriuretic effects. CNP-22 acts by binding and stimulating NPR2 to produce cGMP, and it binds the clearance receptor NPR3. This information is based on the following sources: UniProtKB:Q61839, PubMed:11533490, PubMed:1672777, and PubMed:21098034.

NPPC is also known as CNP, CNP2.

Associated Diseases

• Eiken syndrome
• acromesomelic dysplasia 2B
• spondyloepimetaphyseal dysplasia, Isidor-Toutain type
• chondrodysplasia punctata, tibial-metacarpal type
• fibular aplasia-ectrodactyly syndrome
• pseudoachondroplasia
• Gollop-Wolfgang complex
• spondyloepimetaphyseal dysplasia, Missouri type