NOL11
Description
The NOL11 (nucleolar protein 11) is a protein-coding gene located on chromosome 17.
NOL11 is a ribosomal biogenesis factor, playing a crucial role in both optimal ribosomal DNA (rDNA) transcription and the processing of small subunit (SSU) pre-ribosomal RNA (pre-rRNA). This processing occurs at specific sites within the pre-rRNA molecule, including A', A0, 1, and 2b.
NOL11 is also known as -.
Associated Diseases
- type 2 diabetes mellitus
- prurigo
- hereditary North American Indian childhood cirrhosis
- Treacher-Collins syndrome
