NKX2 1


Description

The NKX2-1 gene, also known as thyroid transcription factor 1 (TTF-1), is a crucial player in the development and function of the thyroid gland. It encodes a transcription factor that binds to specific DNA sequences, activating or repressing the expression of genes involved in thyroid cell differentiation, growth, and hormone production. Mutations in NKX2-1 can lead to various thyroid disorders, highlighting its critical role in thyroid health.

Associated Diseases

Did you know?

NKX2-1 is also expressed in the central nervous system, specifically in the lung and pituitary gland, suggesting its involvement in other developmental processes.


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