NIT2
Description
The NIT2 (nitrilase family member 2) is a protein-coding gene located on chromosome 3.
NIT2 exhibits omega-amidase activity, which is essential for removing potentially harmful intermediates. Specifically, it converts 2-oxoglutaramate and 2-oxosuccinamate into the biologically beneficial 2-oxoglutarate and oxaloacetate, respectively. This activity has been confirmed through experimental evidence (PubMed:19595734, PubMed:22674578).
NIT2 is also known as HEL-S-8a.
