NIPSNAP1

Description

The NIPSNAP1 (nipsnap homolog 1) is a protein-coding gene located on chromosome 22.

NIPSNAP1 (NipSnap1) plays a critical role in the process of mitophagy, which is the selective removal of damaged mitochondria by autophagy. It acts as a 'eat me' signal, directing the autophagy machinery towards these damaged mitochondria.

NIPSNAP1 is also known as -.

Associated Diseases

• type 2 diabetes mellitus
• cancer
• hemoglobin D disease
• hemoglobin E disease
• overhydrated hereditary stomatocytosis
• microcytic anemia with liver iron overload
• monosomy 7 myelodysplasia and leukemia syndrome 1
• hereditary elliptocytosis
• progressive supranuclear palsy-pure akinesia with gait freezing syndrome
• dehydrated hereditary stomatocytosis
• spinocerebellar ataxia type 27
• familial pseudohyperkalemia
• phenylketonuria