NIF3L1
Description
The NIF3L1 (NGG1 interacting factor 3 like 1) is a protein-coding gene located on chromosome 2.
NIF3-like protein 1 is a protein encoded by the NIF3L1 gene in humans. It has been shown to interact with COPS2.
NIF3L1 may act as a transcriptional corepressor by interacting with COPS2. This interaction suppresses the expression of genes crucial for neuronal differentiation.
NIF3L1 is also known as ALS2CR1, CALS-7, MDS015.
Associated Diseases
- juvenile amyotrophic lateral sclerosis
- amyotrophic lateral sclerosis type 2, juvenile
- Alzheimer disease
- Cowden syndrome 1