NID2
Description
The NID2 (nidogen 2) is a protein-coding gene located on chromosome 14.
Nidogen-2, also known as osteonidogen, is a basal lamina protein of the nidogen family. It was the second nidogen to be described after nidogen-1 (entactin). Both play key roles during late embryonic development. In humans, it is encoded by the NID2 gene.
Nidogen-2 is a cell adhesion glycoprotein found in basement membranes. It interacts with several components of the extracellular matrix, including collagens I and IV, perlecan, and laminin 1. It does not bind to fibulins. Nidogen-2 likely plays a role in interactions between cells and the extracellular matrix.
NID2 is also known as NID-2.
