NFIB
Description
The NFIB gene, located on chromosome 10, encodes a transcription factor called nuclear factor IB. This protein plays a critical role in regulating the expression of various genes involved in cellular growth, differentiation, and development. NFIB acts as a molecular switch, binding to specific DNA sequences and either activating or repressing the transcription of target genes. Its activity is tightly controlled, ensuring proper cellular function and preventing uncontrolled cell proliferation.
Associated Diseases
- Neurofibromatosis type 1 (NF1)
- Spinal muscular atrophy (SMA)
- Cancer (including leukemia, lung cancer, and breast cancer)
- Developmental disorders
- Neurological disorders
Did you know?
NFIB is a highly conserved gene, meaning its sequence is similar across different species, suggesting its importance in fundamental biological processes.
