NCL


Description

The NCL (nucleolin) is a protein-coding gene located on chromosome 2.

NCL may refer to:

Nucleolin is a major protein found within the nucleolus of growing eukaryotic cells. It interacts with chromatin and pre-ribosomal particles, contributing to chromatin decondensation by binding to histone H1. This protein plays a critical role in pre-rRNA transcription and ribosome assembly and may be involved in transcriptional elongation. It exhibits a stronger affinity for RNA oligonucleotides with 5'-UUAGGG-3' repeats compared to telomeric single-stranded DNA 5'-TTAGGG-3' repeats.

NCL is also known as C23, Nsr1.

Associated Diseases



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