NBPF7
nbpf7: A Protein with a Critical Role in Blood Clotting
Description
Neutrophil-activating protein 7 (nbpf7) is a protein expressed by neutrophils, a type of white blood cell that is essential for the body's immune response. nbpf7 is involved in the activation of neutrophils, allowing them to release their antimicrobial contents and attack invading microorganisms.
Associated Diseases
Dysregulation of nbpf7 has been implicated in several diseases, including:
- Sepsis: Severe sepsis is a life-threatening condition characterized by uncontrolled inflammation. nbpf7 levels are elevated in patients with sepsis and may contribute to the excessive inflammation and organ damage.
- Rheumatoid arthritis: Rheumatoid arthritis is an autoimmune disease that causes inflammation and joint damage. nbpf7 has been shown to interact with immune cells in the joints, contributing to the inflammatory response.
- Chronic obstructive pulmonary disease (COPD): COPD is a lung disease characterized by airway inflammation and airflow limitation. nbpf7 has been found to be elevated in the lungs of patients with COPD and may contribute to the airway inflammation.
Did you Know ?
In a study of patients with severe sepsis, researchers found that those with elevated nbpf7 levels had a significantly higher risk of developing acute kidney injury (AKI) compared to those with normal nbpf7 levels. AKI is a common complication of sepsis and can significantly increase the risk of mortality.
