NBAT1
Description
The NBAT1 (neuroblastoma associated transcript 1) is a ncRNA gene located on chromosome 6.
NBAT1 is a gene that encodes the N-terminal acetyltransferase 10 (NAA10) protein. This enzyme plays a vital role in protein synthesis by attaching an acetyl group to the N-terminus of newly synthesized proteins, a process known as N-terminal acetylation. This acetylation is crucial for protein folding, stability, trafficking, and degradation. NBAT1 is essential for normal development and function of the nervous system. Mutations in this gene have been associated with various neurodevelopmental disorders.
NBAT1, also known as NAA10, is a key enzyme responsible for the initiation of protein synthesis. It functions as the N-terminal acetyltransferase, catalyzing the attachment of an acetyl group to the N-terminal amino acid of newly synthesized proteins. This acetylation process is crucial for a wide range of cellular processes, including protein folding, stability, and trafficking. It also plays a role in regulating protein degradation, cellular signaling, and gene expression. Defects in NBAT1 have been linked to various developmental and neurological disorders, highlighting its importance in human health.
NBAT1 is also known as CASC14, NBAT-1.
