MYO15B
Description
The MYO15B (myosin XVB) is a protein-coding gene located on chromosome 17.
MYO15B is a gene that provides instructions for making a protein involved in the development and function of the inner ear. This protein is a type of motor protein that helps to move things within cells. It plays a critical role in the assembly and maintenance of stereocilia, which are hair-like projections on hair cells that are essential for hearing. Mutations in this gene can lead to various forms of hearing loss, including Usher syndrome type 1B, which is characterized by deafness and retinitis pigmentosa.
MYO15B is a motor protein that plays a critical role in the development and function of the inner ear. It is involved in the assembly and maintenance of the stereocilia, hair-like projections on hair cells that are essential for hearing. Mutations in MYO15B can lead to various forms of hearing loss, including Usher syndrome type 1B, a genetic disorder characterized by deafness and retinitis pigmentosa. The protein is known to interact with other proteins in the hair bundle, including MYO7A and PCDH15. These interactions are crucial for maintaining the structural integrity and mechanical function of the stereocilia.
MYO15B is also known as MYO15BP.
Associated Diseases
- congenital myopathy
- colorectal cancer
- breast cancer
- Turner syndrome
- cancer
- autosomal recessive congenital ichthyosis 4B
