MYL12B


Description

The MYL12B (myosin light chain 12B) is a protein-coding gene located on chromosome 18.

MYL12B, the gene encoding the myosin light chain 12B protein, is also known as MLC-B or MRLC2. MYL12B is a regulatory light chain that controls the activity of nonmuscle myosin II. Phosphorylation of MYL12B enhances the ATPase activity of myosin II and promotes the assembly of myosin II filaments.

MYL12B plays a crucial role in regulating contractile activity in both smooth muscle and nonmuscle cells through phosphorylation. This phosphorylation triggers actin polymerization, particularly in vascular smooth muscle. MYL12B is also implicated in essential cellular processes like cytokinesis, receptor capping, and cell locomotion.

MYL12B is also known as MLC-B, MRLC2.

Associated Diseases



Disclaimer: The information provided here is not exhaustive by any means. Always consult your doctor or other qualified healthcare provider with any questions you may have regarding a medical condition, procedure, or treatment, whether it is a prescription medication, over-the-counter drug, vitamin, supplement, or herbal alternative.