MYH4

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Description

The MYH4 (myosin heavy chain 4) is a protein-coding gene located on chromosome 17.

MYH4 is a gene that encodes a protein called myosin-4, also known as myosin, heavy chain 4. This protein is a component of the sarcomere, a structural unit of muscle fibers, and plays a crucial role in muscle contraction.

MYH4 plays a crucial role in muscle contraction.

MYH4 is also known as MYH2B, MyHC-2B, MyHC-IIb.

Associated Diseases

• distal myopathy, Welander type
• tibial muscular dystrophy
• muscular dystrophy, limb-girdle, autosomal recessive 23
• GNE myopathy
• inclusion body myopathy with Paget disease of bone and frontotemporal dementia
• autosomal dominant childhood-onset proximal spinal muscular atrophy without contractures
• autosomal recessive limb-girdle muscular dystrophy type 2H
• exercise intolerance, riboflavin-responsive
• polyglucosan body myopathy type 2
• spinal muscular atrophy, type IV
• myofibrillar myopathy 3
• autosomal dominant distal myopathy
• amyotrophic lateral sclerosis
• autosomal recessive limb-girdle muscular dystrophy type 2P
• Finnish upper limb-onset distal myopathy
• autosomal recessive limb-girdle muscular dystrophy type 2G