MUC16
Description
The MUC16 gene, also known as CA125, encodes a large, heavily glycosylated protein that plays a crucial role in the development of ovarian cancer. MUC16 is a transmembrane protein primarily found on the surface of epithelial cells lining the ovaries, peritoneum, and other organs. Its function involves protecting cells from damage and regulating cell growth and differentiation. However, in the case of ovarian cancer, MUC16 expression is often dysregulated, leading to uncontrolled cell growth and the formation of tumors.
Associated Diseases
Did you know?
Elevated levels of MUC16 in the blood, detected through a CA125 test, are commonly used as a biomarker for ovarian cancer diagnosis and monitoring.
