MSH5-SAPCD1
Description
The MSH5-SAPCD1 (MSH5-SAPCD1 readthrough (NMD candidate)) is a ncRNA gene located on chromosome 6.
MSH5-SAPCD1 is a fusion gene arising from a chromosomal rearrangement involving the MSH5 and SAPCD1 genes. This fusion gene encodes a chimeric protein with domains from both parental genes. Its precise function and biological significance are not yet fully understood. However, the involvement of its constituent genes in DNA mismatch repair and cell cycle control suggests that MSH5-SAPCD1 might play a role in genomic stability and potentially contribute to cancer development.
MSH5-SAPCD1 is a fusion gene resulting from a chromosomal rearrangement, combining the MSH5 and SAPCD1 genes. Its precise function remains unclear, but its involvement in DNA mismatch repair and cell cycle control suggests potential roles in genomic stability and cancer development.
MSH5-SAPCD1 is also known as MSH5-C6orf26.
Associated Diseases
- partial chromosome Y deletion
- spermatogenic failures 50
- male infertility with teratozoospermia due to single gene mutation
- spermatogenic failure 25
- schizophrenia
- spermatogenic failure, X-linked, 2
- spermatogenic failure 61
- spermatogenic failure 74
- spermatogenic failure 73
- spermatogenic failure 48
- 46,XX testicular disorder of sex development
- isochromosomy Yp
