MRPL17
Description
The MRPL17 (mitochondrial ribosomal protein L17) is a protein-coding gene located on chromosome 11.
MRPL17, also known as 39S ribosomal protein L17, mitochondrial, is a protein encoded by the MRPL17 gene. This gene encodes a protein component of the large 39S subunit of the mitochondrial ribosome (mitoribosome). Mammalian mitochondria have their own ribosomes, which are essential for protein synthesis within these organelles. These mitochondrial ribosomes are composed of a small 28S subunit and a large 39S subunit. The protein composition of mitoribosomes differs significantly from prokaryotic ribosomes, and the proteins are often not easily identifiable by sequence homology. MRPL17 is one such protein, contributing to the specific structure and function of the mammalian mitochondrial large ribosomal subunit.
MRPL17, also known as 39S ribosomal protein L17, mitochondrial, is a component of the mitochondrial large ribosomal subunit (mt-LSU) and plays a crucial role in mitochondrial protein synthesis. It interacts with other ribosomal proteins and the 16S rRNA to facilitate the assembly and function of the 39S subunit. This subunit, along with the 28S subunit, forms the complete mitochondrial ribosome (mitoribosome) responsible for translating mitochondrial DNA into proteins essential for cellular respiration.
MRPL17 is also known as L17mt, LIP2, MRP-L17, MRP-L26, RPL17L, RPML26, bL17m.
