MOG
Description
The MOG (myelin oligodendrocyte glycoprotein) is a protein-coding gene located on chromosome 6.
MOG, or Myelin oligodendrocyte glycoprotein, is a human gene. It is involved in the formation and maintenance of the myelin sheath, which insulates nerve fibers in the central nervous system. MOG is also implicated in cell-cell communication and can act as a receptor for rubella virus. Mutations in the MOG gene can lead to MOG antibody disease, an inflammatory demyelinating disease of the central nervous system.
MOG is involved in cell-cell adhesion, and is a minor component of the myelin sheath. It may play a role in the completion and maintenance of the myelin sheath, as well as in cell-cell communication.
MOG is also known as BTN6, BTNL11, MOGIG2, NRCLP7.