MLLT11
Description
MLLT11, also known as AF10, is a gene that plays a vital role in normal hematopoiesis, the process of blood cell formation. It encodes a protein that interacts with other proteins to regulate gene expression. MLLT11 is frequently involved in chromosomal translocations, particularly in acute myeloid leukemia (AML). These translocations lead to the formation of fusion proteins that disrupt normal cell growth and differentiation, contributing to cancer development. Understanding the function of MLLT11 and its role in leukemia is crucial for developing targeted therapies.
Associated Diseases
Did you know?
MLLT11 translocations are often associated with specific subtypes of AML, such as AML with t(10;11) translocation.
