MLLT10
Description
MLLT10, also known as AF10, is a gene that plays a crucial role in normal cell development. It encodes a protein that interacts with other proteins to regulate gene expression. However, mutations or translocations involving MLLT10 can disrupt these processes, leading to uncontrolled cell growth and the development of various cancers, particularly leukemia.
Associated Diseases
- Acute myeloid leukemia (AML)
- Acute lymphoblastic leukemia (ALL)
- Myelodysplastic syndromes (MDS)
- T-cell acute lymphoblastic leukemia (T-ALL)
- Breast cancer
- Prostate cancer
Did you know?
MLLT10 translocations are frequently observed in specific subtypes of leukemia, such as AML with t(10;11) and ALL with t(10;11). These translocations lead to the formation of fusion proteins that contribute to the development of these cancers.
