MIRLET7F2
Description
The MIRLET7F2 (microRNA let-7f-2) is a ncRNA gene located on chromosome X.
MicroRNA let-7f-2, encoded by the MIRLET7F2 gene, plays a crucial role in post-transcriptional regulation of gene expression. It acts as a small non-coding RNA (20-24 nucleotides long) that targets messenger RNAs (mRNAs) to control their stability and translation. This process starts with the transcription of a primary transcript (pri-miRNA) by RNA polymerase II. This primary transcript is then processed by enzymes like Drosha and Dicer to generate the mature microRNA (miRNA). The mature miRNA is incorporated into a complex called RNA-induced silencing complex (RISC) that recognizes target mRNAs through imperfect base pairing with the miRNA. This interaction often leads to translational inhibition or degradation of the target mRNA.
MIRLET7F2 is also known as LET7F2, MIRNLET7F2, let-7f-2.
